A Downing Street spokesman also said COVID-19 cases had more than tripled in the region in two weeks.
Greater Manchester’s all-critically ill (ICU) patients will be taken to coronavirus patients in less than a month “if there is no change” in the region, warned Downing Street.
A spokesman for the prime minister also said that coronavirus cases had tripled in the area in two weeks – as the government was still embroiled in controversy with Greater Manchester Mayor Andy Burnham over plans to limit Tier 3 restrictions in the region.
The cases tripled between September 27 and 12 October.
“Admission to the hospital doubles every nine days. The Intensive Care Unit (ICU) currently stands at 40% of the first wave, because lag for two to three weeks we expect that to be the worst.
The ICU’s ‘Greater’ capacity in Greater Manchester will be taken up on November 12th.”
He added that the government had promised more assistance to workers and firms that would be affected by the tight limits.
Negotiations have been going on for a few days – and have erupted into secrecy late last week – but continue on Monday.
The prime minister put pressure on Mr Burnham and other local leaders to accept that the area needed to enter England’s highest level of measures to curb the spread of COVID-19.
Public Affairs Secretary Robert Jenrick Kay Burley that an agreement would have to be reached by the end of Tuesday or the government could intervene and set limits on non-compliance.
Meanwhile, data from the Greater Manchester Critical Care Network (GMCCN) suggested that some of the 12 hospitals in the region had run out of space on Friday.
Statistics show Stepping Hill Hospital and Salford Royal NHS Foundation Trust are fully operational.
It also showed that Royal Bolton Hospital was 94% operational.
Statistics show that hospitals across Greater Manchester are operating at an average rate of 82%.
“It is not uncommon for 80% to 85% beds to be used at this time of year and our hospitals work together when there are certain pressures in any one area, ensuring the best possible care for patients who need the highest level of ICU support, COVID and other reasons.”
A GMCCN source that the NHS often said they were “strong” when they hit 85%, not 100% full beds.
A spokesman for the NHS in the North West said: “Coronavirus cases are on the rise and it is clearly a very serious condition so it is important that everyone does their best to control the virus.”
Downing Street said on Monday that cases among those over 60 in Manchester “continue to rise”, warning if no action is taken at the critically ill rate that will fill COVID patients on November 8, and the full rise could be four days later.
But there are reports of progress, The Times says the prime minister is willing to donate “tens of millions of pounds” to prevent the uprising, while The Telegraph claims it is worth £ 100m.
Mr Burnham had written to Mr Johnson and other party leaders proposing the Commonwealth debate and voting to “end the situation” and establishing a multi-party agreement on financial support for Tier 3 constituencies.
Mr Jenrick suggested that the agreement could not be reached, and said “the terms of the agreement exist”.
He also pointed out that parts of the South and West Yorkshire could be placed in the highest border group in England, telling Kay Burley “we will be discussing similar issues” with local politicians there.
In total, the UK recorded another 16,171 cases on Sunday as well as 150 COVID-related deaths.
That brings the death toll to 43,579.
But separate statistics from the UK statistics agency show that 58,500 people have died from the virus mentioned in their death certificate.